| Pos. | Title | Artist | Label |
| 1 | PROMISCUOUS | NELLY FURTADO | Mosley/Geffen |
| 2 | UNWRITTEN | NATASHA BEDINGFIELD | Epic |
| 3 | BUTTONS | PUSSYCAT DOLLS FEATURING SNOOP DOGG | A&M/Interscope |
| 4 | HIPS DON'T LIE | SHAKIRA FEATURING WYCLEF JEAN | Epic |
| 5 | TEMPERATURE | SEAN PAUL | VP/Atlantic |
| 6 | OVER MY HEAD(CABLE CAR) | FRAY | Epic |
| 7 | SEXYBACK | JUSTIN TIMBERLAKE | Jive/Zomba |
| 8 | BAD DAY | DANIEL POWTER | Warner Bros. |
| 9 | FAR AWAY | NICKELBACK | Roadrunner/IDJMG |
| 10 | ME & U | CASSIE | Next Selection/Bad Boy/Atlantic |
| 11 | CHECK ON IT | BEYONCE FEATURING SLIM THUG | Columbia |
| 12 | SOS | RIHANNA | Def Jam/IDJMG |
| 13 | YOU'RE BEAUTIFUL | JAMES BLUNT | Atlantic |
| 14 | BE WITHOUT YOU | MARY J. BLIGE | Geffen |
| 15 | LIPS OF AN ANGEL | HINDER | Universal Republic |
| 16 | I WRITE SINS NOT TRAGEDIES | PANIC! AT THE DISCO | Decaydance/Fueled By Ramen/Lava |
| 17 | CRAZY | GNARLS BARKLEY | Downtown/Lava/Atlantic |
| 18 | SO SICK | NE-YO | Def Jam/IDJMG |
| 19 | RIDIN' | CHAMILLIONAIRE FEATURING KRAYZIE BONE | Motown/Universal |
| 20 | WALK AWAY | KELLY CLARKSON | Hollywood |
| 21 | LONDON BRIDGE | FERGIE | A&M/Interscope |
| 22 | WHERE'D YOU GO | FORT MINOR FEATURING HOLLY BROOK | Warner Bros. |
| 23 | AIN'T NO OTHER MAN | CHRISTINA AGUILERA | RCA/RMG |
| 24 | TOO LITTLE TOO LATE | JOJO | Da Family/Blackground/Universal Motown |
| 25 | UNFAITHFUL | RIHANNA | SRP/Def Jam/IDJMG |
| 26 | MY LOVE | JUSTIN TIMBERLAKE | Jive/Zomba |
| 27 | MOVE ALONG | ALL-AMERICAN REJECTS | Interscope |
| 28 | CHASING CARS | SNOW PATROL | Warner Bros. |
| 29 | HOW TO SAVE A LIFE | FRAY | Epic |
| 30 | DIRTY LITTLE SECRET | ALL-AMERICAN REJECTS | Interscope |
| 31 | GRILLZ | NELLY FEATURING PAUL WALL, ALI & GIPP | Derrty/Fo' Reel/Universal |
| 32 | SAVIN' ME | NICKELBACK | Roadrunner/IDJMG |
| 33 | WHAT'S LEFT OF ME | NICK LACHEY | Jive/Zomba |
| 34 | RUN IT! | CHRIS BROWN | Jive/Zomba |
| 35 | STICKWITU | PUSSYCAT DOLLS | A&M/Interscope |
| 36 | MONEY MAKER | LUDACIS FEATURING PHARRELL | DTP/Def Jam/IDJMG |
| 37 | SMACK THAT | AKON FEATURING EMINEM | SRC/Universal Motown |
| 38 | CALL ME WHEN YOU'RE SOBER | EVANESCENCE | Wind-up |
| 39 | EVERYTIME WE TOUCH | CASCADA | Robbins |
| 40 | (WHEN YOU GONNA)GIVE IT UP TO ME | SEAN PAUL FEATURING KEYSHIA COLE | VP/Atlantic |
| 41 | DANCE, DANCE | FALL OUT BOYS | Fueled By Ramen/Island/IDJMG |
| 42 | DO IT TO IT | CHERISH FEATURING SEAN PAUL OF THE YOUNGBLOODZ | Sho'nuff/Capitol |
| 43 | PHOTOGRAPH | NICKELBACK | Roadrunner/IDJMG |
| 44 | BECAUSE OF YOU | KELLY CLARKSON | Hollywood |
| 45 | MS. NEW BOOTY | BUBBA SPARXXX FEATURING YING YANG TWINS & MR. COLLIPARK | New South/Puple Ribbon/Virgin |
| 46 | FERGALICIOUS | FERGIE FEATURING BRANDY 'MS. B.' | A&M/Interscope |
| 47 | I'M N LUV(WIT A STRIPPER) | T-PAIN FEATURING MIKE JONES | Konvict Muzik/Jive/Zomba |
| 48 | DANI CALIFORNIA | RED HOT CHILI PEPPERS | Warner Bros. |
| 49 | SHAKE THAT | EMINEM FEATURING NATE DOGG | Shady/Aftermath/Interscope |
| 50 | BEEP | PUSSYCAT DOLLS FEATURING WILL.I.AM | A&M/Interscope |
| 51 | SHOW STOPPER | DANITY KANE | Bad Boy/Atlantic |
| 52 | SEXY LOVE | NE-YO | Def Jam/IDJMG |
| 53 | YO(EXCUSE ME MISS) | CHRIS BROWN | Jive/Zomba |
| 54 | GALLERY | MARIO VAZQUEZ | Arista |
| 55 | GET UP | CIARA FEATURING CHAMILLIONAIRE | LaFace/Jive/Zomba |
| 56 | IRREPLACEABLE | BEYONCE | Columbia |
| 57 | RIGHT HERE | STAIND | Flip/Atlantic |
| 58 | GOLD DIGGER | KANYE WEST FEATURING JAMIE FOXX | Roc-A-Fella/Def Jam/IDJMG |
| 59 | DON'T FORGET ABOUT US | MARIAH CAREY | Island/IDJMG |
| 60 | U AND DAT | E-40 FEATURING T-PAIN & KANDI GIRL | Reprise |
| 61 | SO WHAT | FIELD MOB FEATURING CIARA | DTP/Geffen |
| 62 | HURT | CHRISTINA AGUILERA | RCA/RMG |
| 63 | SUGAR, WE'RE GOIN' DOWN | FALL OUT BOYS | Fueled By Ramen/Island/IDJMG |
| 64 | SAY GOODBYE | CHRIS BROWN | Jive/Zomba |
| 65 | PUMP IT | BLACK EYED PEAS | Interscope |
| 66 | STUPID GIRLS | PINK | LaFace/Zomba |
| 67 | BLACK HORSE & THE CHERRY TREE | KT TUNSTALL | Relentless/Virgin |
| 68 | PULLIN' ME BACK | CHINGY FEATURING TYRESE | Slot-A-Lot/Capitol |
| 69 | THERE IT GO!(THE WHISTLE SONG) | JUELZ SANTANA | Diplomats/Def Jam/IDJMG |
| 70 | I WANNA LOVE YOU | AKON FEATURING SNOOP DOGG | SRC/Universal Motown |
| 71 | HATE ME | BLUE OCTOBER | Universal Motown |
| 72 | IT'S GOIN' DOWN | YOUNG JOC | Block/Bad Boy South/Atlantic |
| 73 | SNAP YO FINGERS | LIL JON FEATURING E-40 & SEAN PAUL OF THE YOUNGBLOODZ | BME/TVT |
| 74 | WAITING ON THE WORLD TO CHANGE | JOHN MAYER | Columbia |
| 75 | ONE WISH | RAY J | Knockout/Sanctuary |
| 76 | MY HUMPS | BLACK EYED PEAS | Interscope |
| 77 | FOR YOU I WILL(CONFIDENCE) | TEDDY GEIGER | Columbia |
| 78 | WIND IT UP | GWEN STEFANI | Interscope |
| 79 | DEJA VU | BEYONCE FEATURING JAY-Z | Music World/Sony Urban/Columbia |
| 80 | BOSSY | KELIS FEATURING TOO SHORT | Jive/Zomba |
| 81 | LEAN WIT IT, ROCK WIT IT | DEM FRANCHSE BOYZ FEATURING LIL PEANUT & CHARLAY | So So Def/Virgin |
| 82 | IT ENDS TONIGHT | ALL-AMERICAN REJECTS | Doghouse/Interscope |
| 83 | WHEN YOU'RE MAD | NE-YO | Def Jam/IDJMG |
| 84 | WHAT HURTS THE MOST | RASCAL FLATTS | Walt Disney |
| 85 | STARS ARE BLIND | PARIS HILTON | Warner Bros. |
| 86 | COME TO ME | DIDDY FEATURING NICOLE SCHERZINGER | Bad Boy/Atlantic |
| 87 | WHAT YOU KNOW | T.I. | Grand Hustle/Atlantic |
| 88 | CHAIN HANG LOW | JIBBS | Geffen |
| 89 | WALK AWAY(REMEMBER ME) | PAULA DEANDA FEATURING THE DEY | Arista |
| 90 | IF IT'S LOVIN' THAT YOU WANT | RIHANNA | Def Jam/IDJMG |
| 91 | GIMME THAT | CHRIS BROWN FEATURING LIL' WAYNE | Jive/Zomba |
| 92 | A PUBLIC AFFAIR | JESSICA SIMPSON | Columbia |
| 93 | BEVERLY HILLS | WEEZER | Geffen |
| 94 | LAFFY TAFFY | D4L | DeeMoney/Asylum./Atlantic |
| 95 | I'M SPRUNG | T-PAIN | Konvict Muzik/Jive/Zomba |
| 96 | GIRL NEXT DOOR | SAVING JANE | Universal |
| 97 | SHORTIE LIKE MINE | BOW WOW FEATURING CHRIS BROWN & JOHNTA AUSTIN | Columbia |
| 98 | LUXURIOUS | GWEN STEFANI | Interscope |
| 99 | SAY IT RIGHT | NELLY FURTADO | Mosley/Geffen |
| 100 | MANEATER | NELLY FURTADO | Mosley/Geffen |
